（商品説明）

有効成分：クロルプロマジン塩酸塩25mg。

本来は人間用医薬品ですが、以下の症状を抑える治療予防薬として犬、猫にも投与可能。

・長時間乗り物に乗らなければならない場合の酔い止め。

・認知症の症状が出ている老犬や老猫の夜鳴き防止。

有効成分のクロルプロマジン塩酸塩が脳内の感情を司る部分に作用を及ぼし興奮物質であるドーパミン、ノルアドレナリン、セロトニンの過度な分泌を抑制して気分を落ち着かせます。

（使用法）

下記の容量を目安に経口投与

犬：3mg/kgを目安に12時間ごとに経口投与。

猫：3mg/kgを目安に24時間ごとに経口投与。

本剤は投薬している薬の相互関連や投薬対象の犬、猫の症状に投薬結果や副作用の出方に異なる影響を及ぼしますので、かかりつけの獣医師と相談の上、投与されることを強くお勧め致します。

＜注意＞

・本薬剤にアレルギー、過敏症状を起こした場合は投薬を中止して下さい。

・緑内障、低血圧、ショック症状のある動物には使用しないで下さい。

・肝臓、心臓に疾患のある動物、超高齢の動物に使用する場合は十分な注意が必要です。

・本剤はバビルツール酸誘導体、プロプラノロール、エピネフリン、下痢止めなどを使用して場合は相互作用を及ぼす可能性があります。

・副作用としてよだれ、低血圧症、癲癇などがあらわれた場合はかかりつけの獣医師に相談し、その指示を仰いで下さい。

・妊娠中、授乳中の動物への投薬は不可。

（使用期限）

ご注文日より１年以上有効のもの

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Chrolpromazine25mg100tabs

Overview of Chlorpromazine for Canines and Felines

Chlorpromazine, better known as Thorazine® or Ormazine®, is used to reduce nausea and vomiting for dogs and cats.

Chlorpromazine belongs to a class of drugs known as phenothiazine derivatives. Other related drugs in this class include acepromazine and prochlorperazine.

The exact mechanism of action of the phenothiazine derivatives is not completely understood. The drugs work by somehow blocking dopamine receptors in the nervous system and may even inhibit the release of dopamine.

These drugs are thought to affect the part of the brain responsible for controlling body temperature, metabolic rate, vomiting, blood pressure and alertness.

Compared to other phenothiazines, chlorpromazine has moderate sedative effects and moderate to strong anti-vomiting effects.

Chlorpromazine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.

This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug.

Uses of Chlorpromazine for Dogs and Cats

Chlorpromazine is used to reduce nausea and vomiting.

Infrequently, chlorpromazine may be used as a sedative. It can also be used to treat motion sickness in cats.

Precautions and Side Effects

While generally safe and effective when prescribed by a veterinarian, chlorpromazine can cause side effects in some animals.

Chlorpromazine should not be used in animals with known hypersensitivity or allergy to the drug.

Chlorpromazine should be avoided in animals with glaucoma, low blood pressure or shock.

This drug should be used with caution in animals with liver disease, heart disease or older patients.

Chlorpromazine may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with chlorpromazine. Such drugs include certain narcotics, barbiturates, propranolol, epinephrine and some anti-diarrheal medications.

Constipation, sedation and low blood pressure may occur after administration of chlorpromazine.

In cases of overdose, chlorpromazine can cause tremors and drooling.

Dosing Information of Chlorpromazine for Cats and Dogs

Medication should never be administered without first consulting your veterinarian.

To treat nausea and vomiting in dogs, chlorpromazine is dosed at 0.12 to 0.25 mg per pound (0.25 to 0.5 mg/kg) subcutaneously or intramuscular every 6 to 24 hours. It can also be given intravenous at a dose of 0.02 to 0.05 mg per pound (0.05 to 0.1 mg/kg) every 6 to 8 hours as needed.

To treat nausea and vomiting in cats, chlorpromazine is dosed at 0.005 to 0.012 mg per pound (0.01 to 0.025 mg/kg) intravenous every 6 to 8 hours as needed.

If vomiting is not severe, chlorpromazine can be administered orally at a dose of 0.05 to 1 mg per pound (0.1 to 2.2 mg/kg) 1 to 4 times daily.

For sedation, chlorpromazine is dosed at 1.5 mg per pound (3 mg/kg) by mouth once or twice daily. The injectable sedative dose is 0.25 mg per pound (0.5 mg/kg) intramuscular or intravenous once or twice daily.

Lower doses are generally recommended in geriatric or sick debilitated pets and those with liver or heart disease.

The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance.