本品は獣医師様及び日本税関で止められた際、ご自身で通関手続きが可能な方、もしくは弊社による通関手続き代行料として別途3900円(数量6点まで)をお支払い頂いたお客様のみに発送致します。

(1)獣医師様は、日本税関で止められましても、通関手続きなし(フリーパス)で問題なく商品がお受け取りできます。

(2)獣医師様以外の方は、税関で止められた場合、通関手続きが必要になりますが、手続きをされることでお受け取りが可能です。獣医師様以外のお客様がご自身で税関対応される場合は獣医師様発行の処方箋が必要になります。

(3)獣医師様以外のご自身での税関対応が不可のお客様には手続き代行料として別途3900円(数量6点まで)をお支払い頂きましたら、弊社側で手続き代行し、お手元にお届け致します。

<備考>

(1)、(2)に該当するお客様に関しまして税関対応・通関手続きの具体的な方法は、日本税関で止められた場合にご連絡差し上げます。

(3)に該当するお客様に関しましてはご注文後、自動送信で送られてくる確認メールに「税関対応依頼」と記載し、返信頂ければ、こちらから改めてご連絡差し上げます。

詳細はこちら→注射液のご注文につきまして。

(商品説明)

犬、猫用短期麻酔薬。

医療処置時に短期間(最大5分)の麻酔が必要な場合の短期全身麻酔薬。

雌犬の帝王切開時における導入麻酔、追加注射される主麻酔のサポート、吸入麻酔の導入麻酔として使用されます。

有効成分:プロポフォール50mg/ml。

 

(使用法)

短期間の麻酔効果を達成するため、麻酔効果が得られるまで、動物の体重に合わせ以下の容量を目安に10-60秒間かけて静脈内に1回、注射します。

犬:鎮静剤が前投薬されていない場合→0.65ml/kg

         鎮静剤が前投薬されている場合→0.4ml/kg

猫:鎮静剤が前投薬されていない場合→0.8ml/kg

         鎮静剤が前投薬されている場合→0.6ml/kg

30分ほどの全身麻酔の効果を得るには最大で2.4ml/kg(24mg/kg)をボーラス投与することも可能です。

吸入麻酔の前には誘導麻酔剤は短期麻酔としての容量で使用し、麻酔ガスの一時濃度は誘導麻酔薬としてバルビツール塩酸を使用する場合よりも高くする必要があります。

 

(麻酔前の鎮静のための前投薬としては通常、以下の薬剤が以下の容量を目安に使用されます。)

アセプロマジン:0.06mg/kg→筋肉内、皮下、静脈注射

オキシモルフォン:0.09mg/kg→筋肉内、皮下、静脈注射

キシラジン:0.33mg/kg→筋肉内、皮下注射

<使用上の注意>

・当薬剤の過剰摂取は短期間の無呼吸、低血圧、徐脈を引き起こす可能性があります。

このような場合は人工呼吸や対症療法の処置を施す必要があります。

・当薬剤の対する過敏症、心臓血管系や呼吸器系に重度の疾患をもった動物には使用しないでください。

・血液量が少ない、腎臓、肝臓、肺に疾患を持っている動物に投与する際は細心の注意が必要です。

・生産用(食用やミルクなどを提供する動物)としての動物には使用しないでください。

・推奨用量に従い投与する限りは通常、動物は耐えれますが、本剤の導入時、また全身麻酔の他の薬は短期間の無呼吸状態や血圧低下、徐脈を引き起こす可能性があります。この場合は人工呼吸や対症療法の処置を講ずる必要があります。

・開封後、5―25度の温度の直射日光の当たらない場所に保管されている条件で28日間有効です。

 

(使用期限)

ご注文日より1年以上有効のもの

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We are going to ship this item only to vets and orderers who go throug costoms if the parcel is stopped by Custom.

(1)Vets can receive this item without any procedure.

(2)Orderes who are not vets need to make customs clearance procedures and they need a prescription issued by a vet.

Propofol 10mg/ml, 50ml injectable for dogs and cats

Description

CONTACTIONS

1 ml of the preparation contains

the active ingredient:Propofol – 10 mg.

PHARMACOLOGICAL PROPERTIES

Refers to the group of preparations for non-inhalation anaesthesia, a sedative of ultra-short effect.

Propofol – the active substance of the drug – is characterized by high lipophilicity and easily penetrates through the hematoencephalic barrier, causing a rapid short-term anesthetic effect with minimal excitation stage manifestations.

Within 30-60 seconds, medication sleep occurs, the development of which is due to the nonspecific effect of propofol on the ionic tubules of the central nervous system membrane neurons. Anesthetic effect after a single administration of the drug in the recommended dose is up to 8 min.

With the support of anesthesia in the usual mode there is no significant cumulation of the drug.

After intravenous administration, propofol binds to plasma proteins (98%), is metabolized mainly in the liver by conjugation with the formation of inactive metabolites, which are excreted mainly from the urine (approx. 88%).

The half-life period in the initial rapid phase of propofol distribution is 1-8 minutes, in the slow phase of distribution – 30-70 minutes, and in the elimination phase from 4 to 23.5 hours.

Propofol is used together with atropine, glycopyrolate, acepromazine, xylazine, ketamine, oxymorphone, halothane and isoflurane. Pharmacological incompatibility is not observed.

APPLICATION

Use dogs and cats for general short-term anaesthesia (especially when a short period of anesthesia is needed), for introductory anaesthesia and to maintain basic anaesthesia. The drug can be used for introductory anesthesia in C-section in bitches.

Animals are injected in the following cases: for short anesthesia in case of short-term (up to 5 minutes) surgical and diagnostic procedures – once, for introductory anesthesia and support of the main anesthesia by additional injections, for introductory anesthesia in inhalation anesthesia.

 

DOSE

To achieve short-term anesthesia, the drug is administered intravenously in a dose designed for animal body weight, once for 10-60 seconds until anesthesia is obtained.

The recommended doses per animal of the appropriate weight are presented in Table 1. In practice, to achieve adequate anesthesia, the dose should be adjusted based on the animal’s response to the drug.

TABLE 1. DOSAGE OF RELAX

ANIMAL SPECIES              TYPE OF ANESTHESIA      THE DOSE OF RELAX BASED ON KG OF ANIMAL BODY WEIGHT

Dogs : Short-term general anesthesia:  

without sedation→0.65 ml (6.5 mg propofol)

with sedation→ 0.4 ml (4 mg propofol)

Cats :Short-term general anesthesia:  

without sedation →0.8 ml (8 mg propofol)

with sedation  → 0.6 ml (6 mg propofol)

For premedication, the following doses are usually used: acepromazine, oxymorphone, xylazine, according to the dosage given in Table 2. Other sedatives, sedatives, opioids and/or α-2-agonists may be used as premedication.

TABLE 2. DOSAGE OF DRUGS FOR SEDATION

PREMEDICATION              DOSE (MG / KG) *            ROUTE OF ADMINISTRATION

Acepromazine          0,060            Intramuscularly, subcutaneously, intravenously

Oxymorphone           0,090                              Intramuscularly, subcutaneously, intravenously

Xylazine                                    0.33                                Intramuscularly, subcutaneously

The doses of these preparations are lower than the normalized doses of the leaflets (instructions) for their use as monotherapies.

General anesthesia lasting up to 30 minutes is provided by induction of anesthesia with the preparation and further bolus injection of additional doses of the preparation, in total up to 2.4 ml/kg of body weight (24 mg/kg of propofol).

Before inhalation anesthesia, the induction anesthesia preparation is used in the same doses as for short-term anesthesia, and the primary concentration of anesthetic gas should be higher when using the preparation than when using barbiturates as an induction anesthetic.

OVERDOSE (SYMPTOMS, EMERGENCY MEASURES, ANTIDOTES)

An overdose of the drug can cause short-term apnea, low blood pressure, bradycardia. In these cases, resort to artificial ventilation of the lungs, prescribe means of symptomatic and pathogenetic therapy.

CONTRAINDICATIONS

Hypersensitivity of the animal to the components of the drug (including anamnesis), severe decompensated diseases of the cardiovascular and respiratory systems. should not be used for anesthesia in pregnant females (if it is planned to preserve the fetus). The drug may be used for induction anaesthesia when performing C-section in bitches.

It is necessary to use the drug with caution in exhausted animals, in hypovolemia, kidney, liver and lung diseases.

Do not use it on productive animals!

SIDE EFFECT

When used according to the recommendations, the inset sheet is usually well tolerated by the animals. Introduction of the drug, as well as other drugs for general anesthesia, may cause short-term apnea in the animal, lowering blood pressure, bradycardia. In these cases, they resort to artificial ventilation of the lungs, prescribe means of symptomatic and pathogenetic therapy.

CAVEATS

Do not freeze!

Do not mix the drug with other drugs in one syringe!

The drug is compatible with drugs that are used for premedication, with myorelaxants, inhalation anesthetics and analgesics; undesirable pharmacodynamic interactions are not indicated.

FORM OF GRANDING

Vials made of glass or polymeric materials with 50 ml. volume.

Shelf life -2 years.

After the first selection from the bottle – 28 days, provided that it is stored in a dark place at temperatures from 40-70F (5 to 25 ° C).

STORAGE CONDITIONS

In a dark, inaccessible place for children at temperatures between 40-70F (5 to 25 ° C).

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プロポフォール10mg/ml,50ml注射液/Propofol 10mg/ml, 50ml injectable

  • 品番: 1
  • 在庫: 在庫あり
  • ¥19,900